This study investigates the safety and effects of an investigational medication in people with certain blood cancers, known as hematological malignancies. These include diseases like acute myeloid leukemia (AML) and other related conditions. The purpose is to understand how the medication works in the body and its potential anti-cancer effects.Participants …
This study investigates the efficacy and safety of an investigational medication in adults with Chronic Pruritus of Unknown Origin (CPUO). Chronic pruritus is a condition characterized by severe itching that lasts for a long time. The exact cause is unknown in this study's participants. The study involves two parts, Study …
This study investigates the effect of an investigational medication on heart health in people with Fabry disease. Fabry disease is a genetic disorder that affects the body's ability to break down a certain type of fat, leading to a buildup that can cause various symptoms, including heart problems. The study …
This study investigates the effects of an investigational medication on pain symptoms in people with Fabry disease. Fabry disease is a genetic disorder that affects the body's ability to break down a specific type of fat, leading to symptoms like pain in the hands, feet, and abdomen. The purpose of …
This study investigates the safety and preliminary effectiveness of an investigational medication, SAR445877, for adults with advanced solid tumors that cannot be removed surgically or have spread to other parts of the body. The study has two parts: Part 1 will determine the best dose of the investigational medication, either …
This study investigates the treatment of hemophilia using an investigational medication. Hemophilia is a condition where blood does not clot properly, leading to excessive bleeding. The purpose of this study is to measure how often bleeding episodes occur in male adults and adolescents aged 12 and older with hemophilia A …
This study investigates the long-term safety of an investigational medication in patients with multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. The purpose of this study is to provide continued access to the investigational medication for patients who have completed a previous study with …
This study investigates the use of an investigational medication for adults with moderate-to-severe asthma. Asthma is a condition where the airways in the lungs become narrow and inflamed, making it hard to breathe. The purpose of this study is to look at the long-term safety, tolerability, and effectiveness of the …
This study investigates the effects of an investigational medication as an add-on therapy for adults with moderate-to-severe asthma. Asthma is a condition where the airways in the lungs become swollen and narrow, making it hard to breathe. The purpose of this study is to evaluate how well the investigational medication …
This study investigates the safety and immune response of an investigational vaccine designed to protect against five types of meningococcal bacteria, which can cause serious infections. The study will involve both adolescents and adults.Participants will receive the investigational vaccine and will be monitored for safety and immune response. The study …
