This study investigates the efficacy and safety of an investigational medication in adults with moderate-to-severe rheumatoid arthritis (RA). RA is a long-term disease that causes pain, swelling, and stiffness in the joints. Participants in this study have RA that is not well controlled with methotrexate, a common RA medication, and …
This study investigates an investigational treatment for adults with moderate to severe plaque psoriasis. Plaque psoriasis is a skin condition that causes red, scaly patches on the skin. The purpose of this study is to find the right dose and to check the safety and effectiveness of the investigational treatment. …
The purpose of this study is to investigate the effects of an investigational medication compared to a placebo in treating moderate to severe atopic dermatitis (AD) in participants aged 12 years and older. Atopic dermatitis, also known as eczema, is a skin condition that causes red, itchy, and inflamed skin. …
This study investigates the treatment of moderate-to-severe atopic dermatitis (AD) in individuals who have not responded well to topical treatments. Atopic dermatitis, often called eczema, is a condition that causes the skin to become itchy and inflamed. The purpose of this study is to compare the effects of an investigational …
This study investigates the effectiveness of an investigational medication in delaying the progression of disability in people with non-relapsing secondary progressive multiple sclerosis (nrSPMS). Multiple sclerosis (MS) is a condition where the immune system mistakenly attacks the protective covering of nerves, leading to communication problems between the brain and the …
This study investigates the effectiveness and safety of an investigational medication for people with moderate-to-severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes red, itchy, and inflamed skin. The study is for participants who have not responded well to other treatments, such as biologic medications or oral …
This study investigates treatment options for people with moderate-to-severe atopic dermatitis, a skin condition that causes red, itchy patches. The purpose of the study is to see if participants who responded to an investigational medication in earlier studies can maintain their response by either continuing the same dose or switching …
This study investigates the effectiveness of a digital program designed to help people stop using tobacco products. Tobacco products include items like cigarettes, cigars, e-cigarettes, and other nicotine products. The goal is to compare this digital program to the usual care methods given to people who want to quit using …
This study investigates the effects of an investigational medication in people with chronic rhinosinusitis without nasal polyps (CRSsNP). Chronic rhinosinusitis is a condition where the spaces inside the nose and head (sinuses) are swollen and inflamed for a long time, causing nasal congestion and other symptoms. The purpose of this …
This study investigates the safety and ability to produce antibodies of an investigational pneumococcal conjugate vaccine, known as PCV21, in healthy infants. Antibodies are proteins in the blood that the body uses to fight infections. The study compares PCV21 to an existing 20-valent pneumococcal vaccine when both are given with …
