This study investigates the safety, efficacy, and immune response of an investigational vaccine for acne. Acne vulgaris is a common skin condition that causes inflammation, particularly in teenagers and young adults. It affects millions of people worldwide and can significantly impact quality of life. The purpose of this study is …
This study investigates the effects of an investigational medication or vaccine on a specific condition. The purpose is to understand how the investigational treatment works and its potential effects on participants.Participants will undergo certain study procedures to monitor their health and any changes that occur during the study. These procedures …
This study investigates the effects of using hemofilters and hemodialyzers on cytokine removal during cardiopulmonary bypass in children undergoing heart surgery. Cardiopulmonary bypass is a procedure that helps correct heart problems, but it can cause a reaction in the body called systemic inflammatory response syndrome (SIRS). This reaction involves various …
This study investigates the safety and effects of an investigational medication compared to a placebo in people with liver fibrosis and compensated cirrhosis. Liver fibrosis is a condition where scar tissue forms in the liver due to injury or long-term damage. Compensated cirrhosis means the liver is scarred but still …
This study investigates the effectiveness of two treatments for geographic atrophy, an eye condition that occurs in some older adults. Geographic atrophy is a form of age-related macular degeneration where parts of the retina deteriorate, leading to vision loss. The purpose of this study is to compare two treatments: an …
This study investigates the safety and effects of an investigational medication when given alone or combined with other treatments for cancer. The purpose is to find the best amount of the medication to use. The study focuses on people with solid tumors, which are abnormal cell lumps, that are advanced …
This study investigates the safety and effectiveness of an investigational medication compared to standard chemotherapy treatments. The focus is on patients with metastatic pancreatic ductal adenocarcinoma (PDAC), a type of cancer that has spread from the pancreas to other parts of the body. The study will compare two approaches: the …
This study investigates the interactions between biomarkers of type 2 diabetes (T2DM) and periodontitis (PD). The purpose of this study is to understand how these two conditions might influence each other. Participants will be organized into nine study arms based on their hemoglobin A1c (HbA1c) levels and periodontal disease stages.Participants …
This study investigates the management of Type 1 diabetes, a chronic disease where the body's defense system mistakenly attacks specific cells within the pancreas, which make insulin. Insulin helps control sugar in the blood. When these cells are damaged, they cannot make enough insulin. This means people with Type 1 …
This study investigates cold agglutinin disease (CAD) and cold agglutinin syndrome (CAS), which are conditions where the body's immune system mistakenly attacks its own red blood cells, causing them to clump together at low temperatures. The purpose of this observational study is to collect data from participants with these conditions …
