Who can participate: Individuals aged 18 to 65 years diagnosed with Condition X and meeting specific health criteria are eligible to participate. Key eligibility factors include no prior treatment with similar investigational medications and stable overall health.Study details: Participants will be randomly assigned to receive either the investigational treatment or …
This study investigates treatment options for people with advanced colorectal cancer, specifically those with certain genetic profiles like KRAS, NRAS, and BRAF wild-type. The purpose is to compare how long participants remain free from disease progression and overall survival when treated with investigational medication and chemotherapy versus standard treatments.Participants will …
This study investigates the effectiveness of an investigational medication when used with standard treatment for people with diffuse large B-cell lymphoma (DLBCL). DLBCL is a type of cancer that affects the lymphatic system, which is part of the body's immune system. The study aims to determine if this combination can …
This study investigates the effects of an investigational medication regimen for treating locally advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma (mGEA). Cancer occurs when cells in a part of the body grow uncontrollably. The investigational medications include ABBV-400 and Budigalimab, which are being studied alongside Fluorouracil and Leucovorin, …
This study investigates the effects of an investigational medication administered subcutaneously in adults with nonresponsive celiac disease (NRCD). Celiac disease is a condition where the body's immune system reacts to gluten, a protein found in wheat, barley, and rye, causing damage to the small intestine. Nonresponsive celiac disease occurs when …
This study investigates the improvement of itching (pruritus) in individuals with Lichen Simplex Chronicus (LSC), a skin condition characterized by thickened, itchy skin, using investigational injections compared to a placebo. The purpose of this study is to see if the investigational injections can reduce the severity of itching in adults …
This study investigates the safety of an investigational vaccine compared to a licensed vaccine in adults aged 18 to 60 years. The investigational vaccine is being compared to the YF-VAX, a vaccine already approved for use. Participants will be randomized to receive either the investigational vaccine or the YF-VAX in …
This study investigates the treatment of asthma in adults who are at high risk and not currently eligible for biologic treatments. Asthma is a condition where the airways narrow and swell, producing extra mucus, which can make breathing difficult. The purpose of this study is to evaluate the effectiveness, safety, …
This study investigates the safety, tolerability, and effectiveness of using a person's own stem cells for treating severe Sickle Cell Disease (SCD). Sickle Cell Disease is a condition where the red blood cells, which carry oxygen, are shaped like a sickle and can block blood flow. This study aims to …
