This study investigates chronic graft versus host disease (cGVHD), a condition where transplanted donor cells attack the recipient's body after a stem cell or bone marrow transplant. The purpose of this study is to determine if adding an investigational medication to the usual treatment with corticosteroids can improve outcomes for …
This study investigates the effects of an investigational medication given by injection compared to a placebo in adults with moderate to severe hidradenitis suppurativa (HS). Hidradenitis suppurativa is a chronic skin condition that causes small, painful lumps under the skin that can break open and form tunnels. The study aims …
This study investigates treatments for adults with moderate to severe atopic dermatitis (AD), a skin condition that causes itchy and inflamed skin. The study is for those whose condition is not well managed with creams or ointments, or for whom these treatments are not suitable. Participants will be randomly assigned …
This study investigates the effects of an investigational medication compared to a placebo in adults with moderate to severe hidradenitis suppurativa (HS). HS is a chronic skin condition characterized by painful lumps under the skin, often in areas where skin rubs together. The study aims to evaluate the efficacy, safety, …
This study investigates the effectiveness of an investigational medication in treating relapsing forms of multiple sclerosis, a condition where the immune system attacks the protective covering of nerves, leading to communication problems between the brain and the rest of the body. The study compares the investigational medication to a daily …
This study investigates the safety and tolerability of an investigational medication given by injection every two or four weeks in people with Chronic Obstructive Pulmonary Disease (COPD). COPD is a long-term lung disease that makes it hard to breathe. The study aims to gather more information on how safe the …
This study investigates the effects of an investigational medication on young children aged 2 to under 6 years who have uncontrolled asthma or recurrent severe asthmatic wheezing. Asthma is a condition where the airways in the lungs become narrow and swollen, making it hard to breathe. This study will help …
This study investigates the safety and immune response of an investigational vaccine for preventing lower respiratory tract disease caused by respiratory syncytial virus (RSV) and human metapneumovirus (hMPV). These are viruses that can lead to lung infections. The study involves healthy adults aged 18 to 49 years and those 60 …
This study investigates a treatment for bronchiectasis, a long-lasting lung disease. Bronchiectasis is characterized by the enlargement of the air passages in the lungs due to a weakening of the airway walls. This condition can cause symptoms such as shortness of breath, coughing up mucus, wheezing, and frequent lung infections.Participants …
This study investigates the long-term safety and tolerability of an investigational medication in adults with different forms of multiple sclerosis, including relapsing multiple sclerosis (RMS), primary progressive multiple sclerosis (PPMS), and non-relapsing secondary progressive multiple sclerosis (NRSPMS). Multiple sclerosis is a condition where the immune system mistakenly attacks the protective …
