This study investigates the use of an investigational medication in people with chronic immune thrombocytopenia (ITP). ITP is a condition where the immune system mistakenly attacks and destroys platelets, which are cells that help blood clot. This can lead to easy or excessive bruising and bleeding. Participants in this study …
This study investigates the effects of an investigational medication on chronic obstructive pulmonary disease (COPD) in former smokers. COPD is a lung condition that makes it hard to breathe and is often caused by smoking. The study compares the investigational medication with a placebo, which is an inactive substance that …
The purpose of this study is to investigate the effectiveness and safety of an investigational medication compared to a placebo in treating adults with active Systemic Lupus Erythematosus (SLE). SLE is a chronic autoimmune disease where the body's immune system mistakenly attacks healthy tissue, causing inflammation and damage to various …
This study investigates the effects of an investigational medication compared to standard therapy on lung function in adults with moderate to severe asthma. Asthma is a condition where the airways in the lungs become narrow and inflamed, making it hard to breathe. This study aims to see if the investigational …
This study investigates the safety and effects of an investigational medication in people with certain blood cancers, known as hematological malignancies. These include diseases like acute myeloid leukemia (AML) and other related conditions. The purpose is to understand how the medication works in the body and its potential anti-cancer effects.Participants …
This study investigates the efficacy and safety of an investigational medication in adults with Chronic Pruritus of Unknown Origin (CPUO). Chronic pruritus is a condition characterized by severe itching that lasts for a long time. The exact cause is unknown in this study's participants. The study involves two parts, Study …
This study investigates the effect of an investigational medication on heart health in people with Fabry disease. Fabry disease is a genetic disorder that affects the body's ability to break down a certain type of fat, leading to a buildup that can cause various symptoms, including heart problems. The study …
This study investigates the effects of an investigational medication on pain symptoms in people with Fabry disease. Fabry disease is a genetic disorder that affects the body's ability to break down a specific type of fat, leading to symptoms like pain in the hands, feet, and abdomen. The purpose of …
This study investigates the effects of an investigational medication compared to an existing treatment for Gaucher disease Type 3 (GD3). Gaucher disease is a genetic disorder where fatty substances accumulate in certain organs. This study aims to evaluate if the investigational medication can stabilize or improve neurological symptoms and maintain …
This study investigates the safety and preliminary effectiveness of an investigational medication, SAR445877, for adults with advanced solid tumors that cannot be removed surgically or have spread to other parts of the body. The study has two parts: Part 1 will determine the best dose of the investigational medication, either …
