This study investigates an investigational medication for individuals with Type 1 diabetes (T1D). Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells within the pancreas, which make insulin. Insulin helps control sugar in the blood. When these cells are damaged, they cannot make …
Who can participate: Participants aged 10 to 17 who have been diagnosed with the specific condition and meet other health criteria are eligible to participate.Study details: Participants will receive either the investigational treatment or a placebo, which is a substance with no active medication, to compare outcomes. The study involves …
This study investigates the use of integrated PET/MR imaging to detect viable heart muscle in patients with coronary artery disease. The goal is to see if this method can effectively identify living heart tissue, which is crucial for determining the best treatment plan and predicting surgery outcomes. Currently, PET/CT and …
This study investigates the effects and safety of an investigational medication in adults with active rheumatoid arthritis (RA), which is a condition where the immune system mistakenly attacks the joints. The purpose of this study is to compare the investigational medication with a placebo, a substance that looks like the …
This study investigates the safety and effectiveness of an investigational medication for eye conditions. The study focuses on participants with branch retinal vein occlusion (BRVO), diabetic macular edema (DME), or neovascular macular degeneration (NVAMD). The study is divided into two parts: the first part looks at different doses of the …
This study investigates the effects of an investigational medication on individuals with Crohn's disease. Crohn's disease is a long-term condition that causes inflammation in the digestive tract, leading to symptoms like abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition.Participants in the study will receive either the investigational medication or …
This study investigates the effects of an investigational medication on a specific condition. The purpose is to understand how this medication interacts with the body and its potential effects on the condition being studied.Participants will undergo various study procedures, including regular assessments and monitoring. These procedures are designed to gather …
Who can participate: Adults aged 18 to 65 years with a diagnosis of chronic pain for at least six months, who have not responded to standard treatments, are eligible to participate.Study details: Participants will be randomly assigned to receive either the investigational treatment or a placebo. The study will involve …
This study investigates the safety and antitumor activity of an investigational medication combined with pembrolizumab and chemotherapy in people with advanced non-squamous non-small cell lung cancer (NSQ NSCLC). NSQ NSCLC is a type of lung cancer that does not involve the squamous cells and is characterized by uncontrolled cell growth …
This study investigates the safety and effects of an investigational medication for people with advanced or metastatic solid tumors. The purpose is to find out how this medication works alone and in combination with other treatments. The study will look at how the body tolerates the medication and if it …
