This study investigates the safety and effectiveness of an investigational medication given alone or with other anti-cancer treatments. It is for adults aged 18 and older who have metastatic cancers that have been treated before. Metastatic cancer means the cancer has spread from where it started to other parts of …
This study investigates the use of caplacizumab and immunosuppressive therapy for treating immune-mediated thrombotic thrombocytopenic purpura (iTTP). iTTP is a condition where the immune system mistakenly attacks certain proteins in the blood, leading to low platelet levels. This can cause problems like easy bruising and bleeding. The purpose of this …
This study investigates an investigational medication for people with moderate to severe Ulcerative Colitis (UC). UC is a long-term condition that causes inflammation and sores in the colon. The purpose of this study is to understand how well the investigational medication works and how safe it is compared to a …
This study investigates the effects of an investigational medication on adults with moderately to severely active Ulcerative Colitis (UC) who have an eosinophilic phenotype. Ulcerative Colitis is a chronic condition where the colon and rectum become inflamed. The study aims to understand how well the investigational medication works and its …
This study investigates the efficacy and safety of an investigational medication in adults with moderate-to-severe rheumatoid arthritis (RA). RA is a long-term disease that causes pain, swelling, and stiffness in the joints. Participants in this study have RA that is not well controlled with methotrexate, a common RA medication, and …
This study investigates chronic graft versus host disease (cGVHD), a condition that occurs when donor cells attack the recipient's body after a stem cell or bone marrow transplant. The purpose of this study is to see if adding an investigational medication to the usual treatment with corticosteroids is beneficial for …
This study investigates an investigational treatment for adults with moderate to severe plaque psoriasis. Plaque psoriasis is a skin condition that causes red, scaly patches on the skin. The purpose of this study is to find the right dose and to check the safety and effectiveness of the investigational treatment. …
The purpose of this study is to investigate the effects of an investigational medication compared to a placebo in treating moderate to severe atopic dermatitis (AD) in participants aged 12 years and older. Atopic dermatitis, also known as eczema, is a skin condition that causes red, itchy, and inflamed skin. …
This study investigates the treatment of moderate-to-severe atopic dermatitis (AD) in individuals who have not responded well to topical treatments. Atopic dermatitis, often called eczema, is a condition that causes the skin to become itchy and inflamed. The purpose of this study is to compare the effects of an investigational …
This study investigates the effectiveness and safety of an investigational medication for people with moderate-to-severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes red, itchy, and inflamed skin. The study is for participants who have not responded well to other treatments, such as biologic medications or oral …
