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Investigating the Impact of Exercise Training on Patients with Heart Infection (Infective Endocarditis)
Study Overview
<p>Can the health of patients with Infective endocarditis (IE) be improved by participation in the physical exercise training within cardiac rehabilitation program?</p><p>Participants will:</p><ul><li>Be physically evaluated by a physiotherapist before and after the progam of physical exercise training within cardiac rehabilitation.</li><li>Do individual exercises in a group led by a physiotherapist 2 times weekly during 12 weeks.</li><li>Answer digitally surveys on the perceived health for 4 times during 1 year</li><li>Participate in interviews on patient's experiences of health and rehabilitation 1 time before and 2 times after the training program during I year.</li></ul>
Study Details
<p>Infective endocarditis (IE) is a rare but severe infectious disease of the heart. Patients with IE are treated for weeks in the hospital and have profound impairments of health for a long time after the treatment. Patients experience a delayed recovery after discharge both physically, with wasting and fatigue; and mentally, with anxiety and depression. Patients suffer from a diminished quality of life and have difficulties returning to work, up to a year post-discharge. Little is known about how patients perceive the IE disease after discharge and if patient&x27;s health can be promoted by rehabilitation since no studies have been able to evaluate the effect of interventions aimed at relieving these problems.</p><p>The hypothesis is that physical exercise training within cardiac rehabilitation can improve physical capacity and reduce symptoms of fatigue. Other aspects of quality of life, mental health, self-rated health and the impact on anxiety and depression will also be studied.</p><p>The investigators aim to study the intervention of physical exercise training within cardiac rehabilitation on the group of patients with IE. The patients with IE will be offered physical exercise training within cardiac rehabilitation according to the protocols of SEPHIA (Secondary Prevention after Heart Intensive Care Admission), as documented in SWEDEHEART(Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies).</p><p>Individualized center-based evaluations according to the protocols are performed before and after the rehabilitation period. Exercises and training are performed in groups led by specialized physiotherapists 2 times per week for 12 weeks. Surveys on health-related quality of life, symptoms of fatigue, anxiety, depression, and occupational balance are digitally distributed at 4 occasions during 1 year after IE. Qualitative interviews will be used 3 times the first year to evaluate the effect and meaning of the program on health and well-being.</p><p>Both the patients&x27; physical improvements for 1 year after IE ( by physiotherapeutic testing) as well as the self-reported experiences of symptoms of fatigue and other aspects of health-related quality of life by surveys will be studied. The patients are also interviewed on expectations and experiences of the intervention and what the patients think is the optimal strategy to regain health. A mixed methods design is chosen to include both quantitative and qualitative data to evaluate the intervention.</p><p>50 patients treated for IE will be included in the study.</p>
Eligibility Criteria
You may be eligible for this study if you meet the following criteria:
- Conditions: Diabetes
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Age: 100 years or below
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Gender: All
<p>Inclusion Criteria:</p><p>Patients with pathological diagnosis of PCD [e.g.: symptomatic/asymptomatic multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), POEMS syndrome, light chain (AL) amyloidosis) from 2007 to 2027 in Zhonshan Hospital.</p><p>Patients who had complete diagnostic, treatment and follow-up records. With fully comprehension and signature of the informed consent form (ICF) for participation.</p><p>Exclusion Criteria:</p><p>Patients who refused to use reliable methods of contraception during pregnancy, lactation or age-appropriate period.</p><p>Patients who suffered from severe mental illness. Patients who were deemed unsuitable for inclusion by the investigator.</p>
This study investigates how participating in a physical exercise training program within cardiac rehabilitation can affect patients with Infective Endocarditis (IE). Infective Endocarditis is a serious infection of the heart that requires extended hospital treatment and can lead to long-lasting health issues, including physical weakness and mental health challenges such as anxiety and depression. The study aims to explore if structured rehabilitation can enhance physical capacity and alleviate symptoms like fatigue, thereby improving overall quality of life.
Participants will undergo physical evaluations by a physiotherapist before and after the 12-week exercise program, which involves group sessions led by a physiotherapist twice a week. They will also complete digital surveys on their perceived health four times over a year and participate in interviews about their health experiences before and after the program. This mixed-method approach combines both quantitative and qualitative data to assess the intervention's impact.
- Who can participate: The study includes patients diagnosed with Infective Endocarditis who have complete diagnostic and treatment records and can understand and sign the informed consent form. Patients with severe mental illness or those deemed unsuitable by the investigator are excluded.
- Study details: Participants will engage in group exercise sessions led by physiotherapists twice a week for 12 weeks. They will complete surveys on health-related quality of life and participate in interviews to discuss their experiences. A placebo is not involved in this study.
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